MARK1-RHOU Fusion FISH Probe
The MARK1-RHOU Fusion FISH Probe is used to confirm a fusion of the MARK1 and RHOU genes. The fusion of the MARK1 and RHOU genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MARK1-RHOU-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-RERE | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-REOR | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-REGO | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-REGR | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-REAQ | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-ORRE | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-OROR | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-ORGO | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-ORAQ | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GORE | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GOOR | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GOGO | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GOGR | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GOAQ | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GRRE | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GROR | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GRGO | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GRGR | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-GRAQ | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-AQRE | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-AQOR | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-AQGO | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-AQGR | 20 (40 μL) | 200 μL |
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| MARK1-RHOU-20-AQAQ | 20 (40 μL) | 200 μL |
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MARK1 Gene Summary
The Microtubule Affinity Regulating Kinase 1 (MARK1) gene is located on chr1 :220701567-220837799 at 1q41.
Gene Name: Microtubule Affinity Regulating Kinase 1
Chromosome: CHR1: 220701567 -220837799
Locus: 1q41
RHOU Gene Summary
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011]
Gene Name: Ras Homolog Family Member U
Chromosome: CHR1: 228780393 -228882416
Locus: 1q42.13
Gene Diseases
The MARK1 RHOU Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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