MAPRE1-USP28 Fusion FISH Probe
The MAPRE1-USP28 Fusion FISH Probe is used to confirm a fusion of the MAPRE1 and USP28 genes. The fusion of the MAPRE1 and USP28 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAPRE1-USP28-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-RERE | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-REOR | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-REGO | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-REGR | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-REAQ | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-ORRE | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-OROR | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-ORGO | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GORE | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GOOR | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GOGO | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GOGR | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GRRE | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GROR | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GRGO | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GRGR | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-AQRE | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-AQOR | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-AQGO | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-AQGR | 20 (40 μL) | 200 μL |
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| MAPRE1-USP28-20-AQAQ | 20 (40 μL) | 200 μL |
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MAPRE1 Gene Summary
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]
Gene Name: Microtubule Associated Protein RP/EB Family Member 1
Chromosome: CHR20: 31407698 -31438211
Locus: 20q11.21
USP28 Gene Summary
The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016]
Gene Name: Ubiquitin Specific Peptidase 28
Chromosome: CHR11: 113668596 -113746256
Locus: 11q23.2
Gene Diseases
The MAPRE1 USP28 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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