MAPRE1-POFUT1 Fusion FISH Probe
The MAPRE1-POFUT1 Fusion FISH Probe is used to confirm a fusion of the MAPRE1 and POFUT1 genes. The fusion of the MAPRE1 and POFUT1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAPRE1-POFUT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-RERE | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-REOR | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-REGO | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-REGR | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-REAQ | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-ORRE | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-OROR | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-ORGO | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GORE | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GOOR | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GOGO | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GOGR | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GRRE | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GROR | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GRGO | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GRGR | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-AQRE | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-AQOR | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-AQGO | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-AQGR | 20 (40 μL) | 200 μL |
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| MAPRE1-POFUT1-20-AQAQ | 20 (40 μL) | 200 μL |
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MAPRE1 Gene Summary
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]
Gene Name: Microtubule Associated Protein RP/EB Family Member 1
Chromosome: CHR20: 31407698 -31438211
Locus: 20q11.21
POFUT1 Gene Summary
This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Protein O-fucosyltransferase 1
Chromosome: CHR20: 30795695 -30826467
Locus: 20q11.21
Gene Diseases
The MAPRE1 POFUT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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