MAPKAPK5-UNC119B Fusion FISH Probe
The MAPKAPK5-UNC119B Fusion FISH Probe is used to confirm a fusion of the MAPKAPK5 and UNC119B genes. The fusion of the MAPKAPK5 and UNC119B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAPKAPK5-UNC119B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-RERE | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-REOR | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-REGO | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-REGR | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-REAQ | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-ORRE | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-OROR | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-ORGO | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GORE | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GOOR | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GOGO | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GOGR | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GRRE | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GROR | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GRGO | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GRGR | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-AQRE | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-AQOR | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-AQGO | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-AQGR | 20 (40 μL) | 200 μL |
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| MAPKAPK5-UNC119B-20-AQAQ | 20 (40 μL) | 200 μL |
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MAPKAPK5 Gene Summary
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
Gene Name: Mitogen-activated Protein Kinase-activated Protein Kinase 5
Chromosome: CHR12: 112280278 -112331228
Locus: 12q24.12-q24.13
UNC119B Gene Summary
The Unc-119 Lipid Binding Chaperone B (UNC119B) gene is located on chr12 :121147830-121161443 at 12q24.31.
Gene Name: Unc-119 Lipid Binding Chaperone B
Chromosome: CHR12: 121147830 -121161443
Locus: 12q24.31
Gene Diseases
The MAPKAPK5 UNC119B Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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