MAP7-ZBTB20 Fusion FISH Probe
The MAP7-ZBTB20 Fusion FISH Probe is used to confirm a fusion of the MAP7 and ZBTB20 genes. The fusion of the MAP7 and ZBTB20 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP7-ZBTB20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-RERE | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-REOR | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-REGO | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-REGR | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-OROR | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GORE | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GROR | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP7-ZBTB20-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP7 Gene Summary
The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Microtubule Associated Protein 7
Chromosome: CHR6: 136663418 -136871957
Locus: 6q23.3
ZBTB20 Gene Summary
This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]
Gene Name: Zinc Finger And BTB Domain Containing 20
Chromosome: CHR3: 114056946 -114866127
Locus: 3q13.31
Gene Diseases
The MAP7 ZBTB20 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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