MAP7-OPRM1 Fusion FISH Probe
The MAP7-OPRM1 Fusion FISH Probe is used to confirm a fusion of the MAP7 and OPRM1 genes. The fusion of the MAP7 and OPRM1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP7-OPRM1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-RERE | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-REOR | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-REGO | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-REGR | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-OROR | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GORE | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GROR | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP7-OPRM1-20-AQAQ | 20 (40 μL) | 200 μL |
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OPRM1 Gene Summary
This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]
Gene Name: Opioid Receptor Mu 1
Chromosome: CHR6: 154360442 -154568001
Locus: 6q25.2
MAP7 Gene Summary
The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene Name: Microtubule Associated Protein 7
Chromosome: CHR6: 136663418 -136871957
Locus: 6q23.3
Gene Diseases
The MAP7 OPRM1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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