MAP4-ULK2 Fusion FISH Probe
The MAP4-ULK2 Fusion FISH Probe is used to confirm a fusion of the MAP4 and ULK2 genes. The fusion of the MAP4 and ULK2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP4-ULK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-RERE | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-REOR | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-REGO | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-REGR | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-OROR | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GORE | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GROR | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP4-ULK2-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP4 Gene Summary
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: Microtubule Associated Protein 4
Chromosome: CHR3: 47892179 -48130769
Locus: 3p21.31
ULK2 Gene Summary
This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2008]
Gene Name: Unc-51 Like Autophagy Activating Kinase 2
Chromosome: CHR17: 19674142 -19771239
Locus: 17p11.2
Gene Diseases
The MAP4 ULK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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