MAP4-GTF2H5 Fusion FISH Probe
The MAP4-GTF2H5 Fusion FISH Probe is used to confirm a fusion of the MAP4 and GTF2H5 genes. The fusion of the MAP4 and GTF2H5 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP4-GTF2H5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-RERE | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-REOR | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-REGO | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-REGR | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-OROR | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GORE | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GROR | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP4-GTF2H5-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP4 Gene Summary
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: Microtubule Associated Protein 4
Chromosome: CHR3: 47892179 -48130769
Locus: 3p21.31
GTF2H5 Gene Summary
This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. [provided by RefSeq, Mar 2009]
Gene Name: General Transcription Factor IIH Subunit 5
Chromosome: CHR6: 158589378 -158620376
Locus: 6q25.3
Gene Diseases
The MAP4 GTF2H5 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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