MAP4-CHD1 Fusion FISH Probe
The MAP4-CHD1 Fusion FISH Probe is used to confirm a fusion of the MAP4 and CHD1 genes. The fusion of the MAP4 and CHD1 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP4-CHD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-RERE | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-REOR | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-REGO | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-REGR | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-OROR | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GORE | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GROR | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP4-CHD1-20-AQAQ | 20 (40 μL) | 200 μL |
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CHD1 Gene Summary
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]
Gene Name: Chromodomain Helicase DNA Binding Protein 1
Chromosome: CHR5: 98190907 -98262238
Locus: 5q15-q21.1
MAP4 Gene Summary
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Name: Microtubule Associated Protein 4
Chromosome: CHR3: 47892179 -48130769
Locus: 3p21.31
Gene Diseases
The MAP4 CHD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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