MAP3K2-IWS1 Fusion FISH Probe
The MAP3K2-IWS1 Fusion FISH Probe is used to confirm a fusion of the MAP3K2 and IWS1 genes. The fusion of the MAP3K2 and IWS1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP3K2-IWS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-RERE | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-REOR | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-REGO | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-REGR | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-OROR | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GORE | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GROR | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP3K2-IWS1-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP3K2 Gene Summary
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase Kinase Kinase 2
Chromosome: CHR2: 128056244 -128100805
Locus: 2q14.3
IWS1 Gene Summary
The IWS1, SUPT6H Interacting Protein (IWS1) gene is located on chr2 :128238382-128284087 at 2q14.3.
Gene Name: IWS1, SUPT6H Interacting Protein
Chromosome: CHR2: 128238382 -128284087
Locus: 2q14.3
Gene Diseases
The MAP3K2 IWS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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