MAP3K13-NSUN2 Fusion FISH Probe
The MAP3K13-NSUN2 Fusion FISH Probe is used to confirm a fusion of the MAP3K13 and NSUN2 genes. The fusion of the MAP3K13 and NSUN2 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP3K13-NSUN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-RERE | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-REOR | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-REGO | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-REGR | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-OROR | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GORE | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GROR | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP3K13-NSUN2-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP3K13 Gene Summary
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase Kinase Kinase 13
Chromosome: CHR3: 185000728 -185206882
Locus: 3q27.2
NSUN2 Gene Summary
This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]
Gene Name: NOP2/Sun RNA Methyltransferase Family Member 2
Chromosome: CHR5: 6599351 -6633473
Locus: 5p15.31
Gene Diseases
The MAP3K13 NSUN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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