MAP3K10-SUPT5H Fusion FISH Probe
The MAP3K10-SUPT5H Fusion FISH Probe is used to confirm a fusion of the MAP3K10 and SUPT5H genes. The fusion of the MAP3K10 and SUPT5H genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP3K10-SUPT5H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-RERE | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-REOR | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-REGO | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-REGR | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-OROR | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GORE | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GROR | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP3K10-SUPT5H-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP3K10 Gene Summary
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase Kinase Kinase 10
Chromosome: CHR19: 40697650 -40721482
Locus: 19q13.2
SUPT5H Gene Summary
The SPT5 Homolog, DSIF Elongation Factor Subunit (SUPT5H) gene is located on chr19 :39936185-39967308 at 19q13.2.
Gene Name: SPT5 Homolog, DSIF Elongation Factor Subunit
Chromosome: CHR19: 39936185 -39967308
Locus: 19q13.2
Gene Diseases
The MAP3K10 SUPT5H Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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