MAP2K1-CUX1 Fusion FISH Probe
The MAP2K1-CUX1 Fusion FISH Probe is used to confirm a fusion of the MAP2K1 and CUX1 genes. The fusion of the MAP2K1 and CUX1 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP2K1-CUX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-RERE | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-REOR | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-REGO | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-REGR | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-OROR | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GORE | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GROR | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP2K1-CUX1-20-AQAQ | 20 (40 μL) | 200 μL |
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CUX1 Gene Summary
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011]
Gene Name: Cut Like Homeobox 1
Chromosome: CHR7: 101459183 -101927250
Locus: 7q22.1
MAP2K1 Gene Summary
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase Kinase 1
Chromosome: CHR15: 66679210 -66783882
Locus: 15q22.31
Gene Diseases
The MAP2K1 CUX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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