MAP1S-ECH1 Fusion FISH Probe
The MAP1S-ECH1 Fusion FISH Probe is used to confirm a fusion of the MAP1S and ECH1 genes. The fusion of the MAP1S and ECH1 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP1S-ECH1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-RERE | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-REOR | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-REGO | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-REGR | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-OROR | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GORE | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GROR | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP1S-ECH1-20-AQAQ | 20 (40 μL) | 200 μL |
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ECH1 Gene Summary
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. [provided by RefSeq, Jul 2008]
Gene Name: Enoyl-CoA Hydratase 1
Chromosome: CHR19: 39306061 -39322497
Locus: 19q13.2
MAP1S Gene Summary
The Microtubule Associated Protein 1S (MAP1S) gene is located on chr19 :17830302-17845324 at 19p13.11.
Gene Name: Microtubule Associated Protein 1S
Chromosome: CHR19: 17830302 -17845324
Locus: 19p13.11
Gene Diseases
The MAP1S ECH1 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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