MAP1B-SUPT16H Fusion FISH Probe
The MAP1B-SUPT16H Fusion FISH Probe is used to confirm a fusion of the MAP1B and SUPT16H genes. The fusion of the MAP1B and SUPT16H genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAP1B-SUPT16H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-RERE | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-REOR | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-REGO | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-REGR | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-REAQ | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-ORRE | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-OROR | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-ORGO | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GORE | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GOOR | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GOGO | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GOGR | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GRRE | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GROR | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GRGO | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GRGR | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-AQRE | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-AQOR | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-AQGO | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-AQGR | 20 (40 μL) | 200 μL |
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| MAP1B-SUPT16H-20-AQAQ | 20 (40 μL) | 200 μL |
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MAP1B Gene Summary
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The product of this gene is a precursor polypeptide that presumably undergoes proteolytic processing to generate the final MAP1B heavy chain and LC1 light chain. Gene knockout studies of the mouse microtubule-associated protein 1B gene suggested an important role in development and function of the nervous system. [provided by RefSeq, Jul 2008]
Gene Name: Microtubule Associated Protein 1B
Chromosome: CHR5: 71403117 -71505397
Locus: 5q13.2
SUPT16H Gene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]
Gene Name: SPT16 Homolog, Facilitates Chromatin Remodeling Subunit
Chromosome: CHR14: 21819630 -21852425
Locus: 14q11.2
Gene Diseases
The MAP1B SUPT16H Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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