MAN2C1-PTPN9 Fusion FISH Probe
The MAN2C1-PTPN9 Fusion FISH Probe is used to confirm a fusion of the MAN2C1 and PTPN9 genes. The fusion of the MAN2C1 and PTPN9 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAN2C1-PTPN9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-RERE | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-REOR | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-REGO | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-REGR | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-REAQ | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-ORRE | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-OROR | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-ORGO | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GORE | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GOOR | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GOGO | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GOGR | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GRRE | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GROR | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GRGO | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GRGR | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-AQRE | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-AQOR | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-AQGO | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-AQGR | 20 (40 μL) | 200 μL |
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| MAN2C1-PTPN9-20-AQAQ | 20 (40 μL) | 200 μL |
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MAN2C1 Gene Summary
The Mannosidase Alpha Class 2C Member 1 (MAN2C1) gene is located on chr15 :75648132-75660941 at 15q24.2.
Gene Name: Mannosidase Alpha Class 2C Member 1
Chromosome: CHR15: 75648132 -75660941
Locus: 15q24.2
PTPN9 Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq, Jul 2008]
Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 9
Chromosome: CHR15: 75759461 -75871625
Locus: 15q24.2
Gene Diseases
The MAN2C1 PTPN9 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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