MAN1A2-TTF2 Fusion FISH Probe
The MAN1A2-TTF2 Fusion FISH Probe is used to confirm a fusion of the MAN1A2 and TTF2 genes. The fusion of the MAN1A2 and TTF2 genes has been associated with Uterine Corpus Endometrial Carcinoma, Uterine Corpus Endometrial Carcinoma, and Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAN1A2-TTF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-RERE | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-REOR | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-REGO | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-REGR | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-REAQ | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-ORRE | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-OROR | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-ORGO | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GORE | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GOOR | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GOGO | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GOGR | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GRRE | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GROR | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GRGO | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GRGR | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-AQRE | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-AQOR | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-AQGO | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-AQGR | 20 (40 μL) | 200 μL |
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| MAN1A2-TTF2-20-AQAQ | 20 (40 μL) | 200 μL |
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TTF2 Gene Summary
This gene encodes a member of the SWI2/SNF2 family of proteins, which play a critical role in altering protein-DNA interactions. The encoded protein has been shown to have dsDNA-dependent ATPase activity and RNA polymerase II termination activity. This protein interacts with cell division cycle 5-like, associates with human splicing complexes, and plays a role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]
Gene Name: Transcription Termination Factor 2
Chromosome: CHR1: 117602948 -117645491
Locus: 1p13.1
MAN1A2 Gene Summary
Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information.[supplied by OMIM, Mar 2008]
Gene Name: Mannosidase Alpha Class 1A Member 2
Chromosome: CHR1: 117910084 -118068320
Locus: 1p12
Gene Diseases
The MAN1A2 TTF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
| Uterine Corpus Endometrial Carcinoma |
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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