MAN1A2-PDE4DIP Fusion FISH Probe
The MAN1A2-PDE4DIP Fusion FISH Probe is used to confirm a fusion of the MAN1A2 and PDE4DIP genes. The fusion of the MAN1A2 and PDE4DIP genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAN1A2-PDE4DIP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-RERE | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-REOR | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-REGO | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-REGR | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-REAQ | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-ORRE | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-OROR | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-ORGO | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GORE | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GOOR | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GOGO | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GOGR | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GRRE | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GROR | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GRGO | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GRGR | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-AQRE | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-AQOR | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-AQGO | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-AQGR | 20 (40 μL) | 200 μL |
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| MAN1A2-PDE4DIP-20-AQAQ | 20 (40 μL) | 200 μL |
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PDE4DIP Gene Summary
The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Gene Name: Phosphodiesterase 4D Interacting Protein
Chromosome: CHR1: 144851423 -145039992
Locus: 1q21.2
MAN1A2 Gene Summary
Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) for general information.[supplied by OMIM, Mar 2008]
Gene Name: Mannosidase Alpha Class 1A Member 2
Chromosome: CHR1: 117910084 -118068320
Locus: 1p12
Gene Diseases
The MAN1A2 PDE4DIP Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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