MAK-INTS12 Fusion FISH Probe
The MAK-INTS12 Fusion FISH Probe is used to confirm a fusion of the MAK and INTS12 genes. The fusion of the MAK and INTS12 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAK-INTS12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-RERE | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-REOR | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-REGO | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-REGR | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-REAQ | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-ORRE | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-OROR | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-ORGO | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GORE | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GOOR | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GOGO | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GOGR | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GRRE | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GROR | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GRGO | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GRGR | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-AQRE | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-AQOR | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-AQGO | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-AQGR | 20 (40 μL) | 200 μL |
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| MAK-INTS12-20-AQAQ | 20 (40 μL) | 200 μL |
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MAK Gene Summary
The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Name: Male Germ Cell Associated Kinase
Chromosome: CHR6: 10762955 -10838788
Locus: 6p24.2
INTS12 Gene Summary
INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Name: Integrator Complex Subunit 12
Chromosome: CHR4: 106603784 -106629881
Locus: 4q24
Gene Diseases
The MAK INTS12 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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