MAGI3-DENND5A Fusion FISH Probe
The MAGI3-DENND5A Fusion FISH Probe is used to confirm a fusion of the MAGI3 and DENND5A genes. The fusion of the MAGI3 and DENND5A genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAGI3-DENND5A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-RERE | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-REOR | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-REGO | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-REGR | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-REAQ | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-ORRE | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-OROR | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-ORGO | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GORE | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GOOR | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GOGO | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GOGR | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GRRE | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GROR | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GRGO | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GRGR | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-AQRE | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-AQOR | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-AQGO | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-AQGR | 20 (40 μL) | 200 μL |
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| MAGI3-DENND5A-20-AQAQ | 20 (40 μL) | 200 μL |
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DENND5A Gene Summary
This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. [provided by RefSeq, Feb 2017]
Gene Name: DENN Domain Containing 5A
Chromosome: CHR11: 9160374 -9286873
Locus: 11p15.4
MAGI3 Gene Summary
The Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 3 (MAGI3) gene is located on chr1 :113933474-114228545 at 1p13.2.
Gene Name: Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 3
Chromosome: CHR1: 113933474 -114228545
Locus: 1p13.2
Gene Diseases
The MAGI3 DENND5A Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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