MAGI2-VWC2 Fusion FISH Probe
The MAGI2-VWC2 Fusion FISH Probe is used to confirm a fusion of the MAGI2 and VWC2 genes. The fusion of the MAGI2 and VWC2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAGI2-VWC2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-RERE | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-REOR | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-REGO | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-REGR | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-REAQ | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-ORRE | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-OROR | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-ORGO | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GORE | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GOOR | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GOGO | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GOGR | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GRRE | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GROR | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GRGO | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GRGR | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-AQRE | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-AQOR | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-AQGO | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-AQGR | 20 (40 μL) | 200 μL |
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| MAGI2-VWC2-20-AQAQ | 20 (40 μL) | 200 μL |
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MAGI2 Gene Summary
The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]
Gene Name: Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 2
Chromosome: CHR7: 77646373 -79082890
Locus: 7q21.11
VWC2 Gene Summary
This gene encodes a secreted bone morphogenic protein antagonist. The encoded protein is possibly involved in neural function and development and may have a role in cell adhesion.[provided by RefSeq, Oct 2009]
Gene Name: Von Willebrand Factor C Domain Containing 2
Chromosome: CHR7: 49813256 -49952138
Locus: 7p12.2
Gene Diseases
The MAGI2 VWC2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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