MAGED2-SCAMP4 Fusion FISH Probe
The MAGED2-SCAMP4 Fusion FISH Probe is used to confirm a fusion of the MAGED2 and SCAMP4 genes. The fusion of the MAGED2 and SCAMP4 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAGED2-SCAMP4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-RERE | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-REOR | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-REGO | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-REGR | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-REAQ | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-ORRE | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-OROR | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-ORGO | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GORE | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GOOR | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GOGO | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GOGR | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GRRE | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GROR | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GRGO | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GRGR | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-AQRE | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-AQOR | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-AQGO | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-AQGR | 20 (40 μL) | 200 μL |
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| MAGED2-SCAMP4-20-AQAQ | 20 (40 μL) | 200 μL |
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MAGED2 Gene Summary
This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked intellectual disability (XLID). Mutations in this gene cause a form of transient antenatal Bartter's syndrome. This gene may also be involved in several types of cancer, including breast cancer and melanoma. The protein encoded by this gene is progressively recruited from the cytoplasm to the nucleoplasm during the interphase and after nucleolar stress and is thus thought to play a role in cell cycle regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
Gene Name: MAGE Family Member D2
Chromosome: CHRX: 54834170 -54842445
Locus: Xp11.21
SCAMP4 Gene Summary
Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 [PubMed 11050114]).[supplied by OMIM, Feb 2011]
Gene Name: Secretory Carrier Membrane Protein 4
Chromosome: CHR19: 1905372 -1926012
Locus: 19p13.3
Gene Diseases
The MAGED2 SCAMP4 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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