MAGED1-CYP4F2 Fusion FISH Probe
The MAGED1-CYP4F2 Fusion FISH Probe is used to confirm a fusion of the MAGED1 and CYP4F2 genes. The fusion of the MAGED1 and CYP4F2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAGED1-CYP4F2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-RERE | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-REOR | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-REGO | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-REGR | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-REAQ | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-ORRE | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-OROR | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-ORGO | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GORE | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GOOR | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GOGO | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GOGR | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GRRE | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GROR | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GRGO | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GRGR | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-AQRE | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-AQOR | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-AQGO | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-AQGR | 20 (40 μL) | 200 μL |
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| MAGED1-CYP4F2-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP4F2 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F11, is approximately 16 kb away. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Family 4 Subfamily F Member 2
Chromosome: CHR19: 15988833 -16008884
Locus: 19p13.12
MAGED1 Gene Summary
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: MAGE Family Member D1
Chromosome: CHRX: 51546154 -51645450
Locus: Xp11.22
Gene Diseases
The MAGED1 CYP4F2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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