MAFF-OSBP2 Fusion FISH Probe
The MAFF-OSBP2 Fusion FISH Probe is used to confirm a fusion of the MAFF and OSBP2 genes. The fusion of the MAFF and OSBP2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAFF-OSBP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| MAFF-OSBP2-20-AQAQ | 20 (40 μL) | 200 μL |
|
OSBP2 Gene Summary
The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Oxysterol Binding Protein 2
Chromosome: CHR22: 31090792 -31303811
Locus: 22q12.2
MAFF Gene Summary
The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
Gene Name: MAF BZIP Transcription Factor F
Chromosome: CHR22: 38597938 -38612517
Locus: 22q13.1
Gene Diseases
The MAFF OSBP2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|