MAD1L1-SERGEF Fusion FISH Probe
The MAD1L1-SERGEF Fusion FISH Probe is used to confirm a fusion of the MAD1L1 and SERGEF genes. The fusion of the MAD1L1 and SERGEF genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MAD1L1-SERGEF-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-RERE | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-REOR | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-REGO | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-REGR | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-REAQ | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-ORRE | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-OROR | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-ORGO | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-ORAQ | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GORE | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GOOR | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GOGO | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GOGR | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GOAQ | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GRRE | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GROR | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GRGO | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GRGR | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-GRAQ | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-AQRE | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-AQOR | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-AQGO | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-AQGR | 20 (40 μL) | 200 μL |
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| MAD1L1-SERGEF-20-AQAQ | 20 (40 μL) | 200 μL |
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MAD1L1 Gene Summary
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: Mitotic Arrest Deficient 1 Like 1
Chromosome: CHR7: 1855427 -2272583
Locus: 7p22.3
SERGEF Gene Summary
The Secretion Regulating Guanine Nucleotide Exchange Factor (SERGEF) gene is located on chr11 :17809596-18034637 at 11p15.1.
Gene Name: Secretion Regulating Guanine Nucleotide Exchange Factor
Chromosome: CHR11: 17809596 -18034637
Locus: 11p15.1
Gene Diseases
The MAD1L1 SERGEF Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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