MACROD1-PARP1 Fusion FISH Probe
The MACROD1-PARP1 Fusion FISH Probe is used to confirm a fusion of the MACROD1 and PARP1 genes. The fusion of the MACROD1 and PARP1 genes has been associated with Uveal Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| MACROD1-PARP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-RERE | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-REOR | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-REGO | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-REGR | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-REAQ | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-ORRE | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-OROR | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-ORGO | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GORE | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GOOR | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GOGO | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GOGR | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GRRE | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GROR | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GRGO | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GRGR | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-AQRE | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-AQOR | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-AQGO | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-AQGR | 20 (40 μL) | 200 μL |
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| MACROD1-PARP1-20-AQAQ | 20 (40 μL) | 200 μL |
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PARP1 Gene Summary
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
Gene Name: Poly(ADP-ribose) Polymerase 1
Chromosome: CHR1: 226548391 -226595801
Locus: 1q42.12
MACROD1 Gene Summary
The MACRO Domain Containing 1 (MACROD1) gene is located on chr11 :63766029-63933585 at 11q13.1.
Gene Name: MACRO Domain Containing 1
Chromosome: CHR11: 63766029 -63933585
Locus: 11q13.1
Gene Diseases
The MACROD1 PARP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uveal Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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