LYZ-NDUFV1 Fusion FISH Probe
The LYZ-NDUFV1 Fusion FISH Probe is used to confirm a fusion of the LYZ and NDUFV1 genes. The fusion of the LYZ and NDUFV1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LYZ-NDUFV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-RERE | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-REOR | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-REGO | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-REGR | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-REAQ | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-ORRE | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-OROR | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-ORGO | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GORE | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GOOR | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GOGO | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GOGR | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GRRE | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GROR | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GRGO | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GRGR | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-AQRE | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-AQOR | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-AQGO | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-AQGR | 20 (40 μL) | 200 μL |
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| LYZ-NDUFV1-20-AQAQ | 20 (40 μL) | 200 μL |
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LYZ Gene Summary
This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014]
Gene Name: Lysozyme
Chromosome: CHR12: 69742133 -69748013
Locus: 12q15
NDUFV1 Gene Summary
The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009]
Gene Name: NADH:ubiquinone Oxidoreductase Core Subunit V1
Chromosome: CHR11: 67374322 -67380012
Locus: 11q13.2
Gene Diseases
The LYZ NDUFV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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