LYZ-DDX21 Fusion FISH Probe
The LYZ-DDX21 Fusion FISH Probe is used to confirm a fusion of the LYZ and DDX21 genes. The fusion of the LYZ and DDX21 genes has been associated with Acute Myeloid Leukemia, and Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LYZ-DDX21-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-RERE | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-REOR | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-REGO | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-REGR | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-REAQ | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-ORRE | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-OROR | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-ORGO | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-ORAQ | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GORE | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GOOR | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GOGO | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GOGR | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GOAQ | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GRRE | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GROR | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GRGO | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GRGR | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-GRAQ | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-AQRE | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-AQOR | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-AQGO | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-AQGR | 20 (40 μL) | 200 μL |
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| LYZ-DDX21-20-AQAQ | 20 (40 μL) | 200 μL |
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LYZ Gene Summary
This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014]
Gene Name: Lysozyme
Chromosome: CHR12: 69742133 -69748013
Locus: 12q15
DDX21 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]
Gene Name: DExD-box Helicase 21
Chromosome: CHR10: 70715891 -70744279
Locus: 10q22.1
Gene Diseases
The LYZ DDX21 Fusion has been associated with the following diseases:
| Disease Name |
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| Acute Myeloid Leukemia |
| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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