LYZ-ANXA1 Fusion FISH Probe
The LYZ-ANXA1 Fusion FISH Probe is used to confirm a fusion of the LYZ and ANXA1 genes. The fusion of the LYZ and ANXA1 genes has been associated with Acute Myeloid Leukemia, and Acute Myeloid Leukemia. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LYZ-ANXA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-RERE | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-REOR | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-REGO | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-REGR | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-REAQ | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-ORRE | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-OROR | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-ORGO | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GORE | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GOOR | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GOGO | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GOGR | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GRRE | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GROR | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GRGO | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GRGR | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-AQRE | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-AQOR | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-AQGO | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-AQGR | 20 (40 μL) | 200 μL |
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| LYZ-ANXA1-20-AQAQ | 20 (40 μL) | 200 μL |
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ANXA1 Gene Summary
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Gene Name: Annexin A1
Chromosome: CHR9: 75766780 -75785307
Locus: 9q21.13
LYZ Gene Summary
This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis. [provided by RefSeq, Oct 2014]
Gene Name: Lysozyme
Chromosome: CHR12: 69742133 -69748013
Locus: 12q15
Gene Diseases
The LYZ ANXA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Acute Myeloid Leukemia |
| Acute Myeloid Leukemia |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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