LYST-SLC3A2 Fusion FISH Probe
The LYST-SLC3A2 Fusion FISH Probe is used to confirm a fusion of the LYST and SLC3A2 genes. The fusion of the LYST and SLC3A2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LYST-SLC3A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-RERE | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-REOR | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-REGO | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-REGR | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-REAQ | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-ORRE | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-OROR | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-ORGO | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GORE | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GOOR | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GOGO | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GOGR | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GRRE | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GROR | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GRGO | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GRGR | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-AQRE | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-AQOR | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-AQGO | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-AQGR | 20 (40 μL) | 200 μL |
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| LYST-SLC3A2-20-AQAQ | 20 (40 μL) | 200 μL |
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LYST Gene Summary
This gene encodes a protein that regulates intracellular protein trafficking in endosomes, and may be involved in pigmentation. Mutations in this gene are associated with Chediak-Higashi syndrome, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants, though the full-length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2013]
Gene Name: Lysosomal Trafficking Regulator
Chromosome: CHR1: 235824344 -236030220
Locus: 1q42.3
SLC3A2 Gene Summary
This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. [provided by RefSeq, Nov 2010]
Gene Name: Solute Carrier Family 3 Member 2
Chromosome: CHR11: 62623483 -62656355
Locus: 11q12.3
Gene Diseases
The LYST SLC3A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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