LYST-NARS2 Fusion FISH Probe
The LYST-NARS2 Fusion FISH Probe is used to confirm a fusion of the LYST and NARS2 genes. The fusion of the LYST and NARS2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LYST-NARS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-RERE | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-REOR | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-REGO | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-REGR | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-REAQ | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-ORRE | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-OROR | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-ORGO | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GORE | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GOOR | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GOGO | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GOGR | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GRRE | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GROR | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GRGO | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GRGR | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-AQRE | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-AQOR | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-AQGO | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-AQGR | 20 (40 μL) | 200 μL |
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| LYST-NARS2-20-AQAQ | 20 (40 μL) | 200 μL |
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LYST Gene Summary
This gene encodes a protein that regulates intracellular protein trafficking in endosomes, and may be involved in pigmentation. Mutations in this gene are associated with Chediak-Higashi syndrome, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants, though the full-length nature of some of these variants has not been determined. [provided by RefSeq, Apr 2013]
Gene Name: Lysosomal Trafficking Regulator
Chromosome: CHR1: 235824344 -236030220
Locus: 1q42.3
NARS2 Gene Summary
This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24). [provided by RefSeq, Mar 2015]
Gene Name: Asparaginyl-tRNA Synthetase 2, Mitochondrial
Chromosome: CHR11: 78147006 -78285909
Locus: 11q14.1
Gene Diseases
The LYST NARS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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