LYRM4-EYS Fusion FISH Probe
The LYRM4-EYS Fusion FISH Probe is used to confirm a fusion of the LYRM4 and EYS genes. The fusion of the LYRM4 and EYS genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LYRM4-EYS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-RERE | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-REOR | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-REGO | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-REGR | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-REAQ | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-ORRE | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-OROR | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-ORGO | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-ORAQ | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GORE | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GOOR | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GOGO | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GOGR | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GOAQ | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GRRE | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GROR | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GRGO | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GRGR | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-GRAQ | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-AQRE | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-AQOR | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-AQGO | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-AQGR | 20 (40 μL) | 200 μL |
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| LYRM4-EYS-20-AQAQ | 20 (40 μL) | 200 μL |
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LYRM4 Gene Summary
The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis. [provided by RefSeq, Sep 2016]
Gene Name: LYR Motif Containing 4
Chromosome: CHR6: 5108652 -5261172
Locus: 6p25.1
EYS Gene Summary
The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Eyes Shut Homolog (Drosophila)
Chromosome: CHR6: 64429875 -66417118
Locus: 6q12
Gene Diseases
The LYRM4 EYS Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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