LYN-NTRK3 Fusion FISH Probe
The LYN-NTRK3 Fusion FISH Probe is used to confirm a fusion of the LYN and NTRK3 genes. The fusion of the LYN and NTRK3 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LYN-NTRK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-RERE | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-REOR | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-REGO | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-REGR | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-REAQ | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-ORRE | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-OROR | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-ORGO | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GORE | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GOOR | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GOGO | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GOGR | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GRRE | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GROR | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GRGO | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GRGR | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-AQRE | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-AQOR | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-AQGO | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-AQGR | 20 (40 μL) | 200 μL |
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| LYN-NTRK3-20-AQAQ | 20 (40 μL) | 200 μL |
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LYN Gene Summary
This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Gene Name: LYN Proto-oncogene, Src Family Tyrosine Kinase
Chromosome: CHR8: 56792385 -56925006
Locus: 8q12.1
NTRK3 Gene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Gene Name: Neurotrophic Receptor Tyrosine Kinase 3
Chromosome: CHR15: 88419987 -88799962
Locus: 15q25.3
Gene Diseases
The LYN NTRK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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