LUC7L3-CACNA1G Fusion FISH Probe
The LUC7L3-CACNA1G Fusion FISH Probe is used to confirm a fusion of the LUC7L3 and CACNA1G genes. The fusion of the LUC7L3 and CACNA1G genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LUC7L3-CACNA1G-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-RERE | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-REOR | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-REGO | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-REGR | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-REAQ | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-ORRE | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-OROR | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-ORGO | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-ORAQ | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GORE | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GOOR | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GOGO | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GOGR | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GOAQ | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GRRE | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GROR | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GRGO | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GRGR | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-GRAQ | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-AQRE | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-AQOR | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-AQGO | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-AQGR | 20 (40 μL) | 200 μL |
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| LUC7L3-CACNA1G-20-AQAQ | 20 (40 μL) | 200 μL |
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CACNA1G Gene Summary
Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division, and cell death. This gene encodes a T-type, low-voltage activated calcium channel. The T-type channels generate currents that are both transient, owing to fast inactivation, and tiny, owing to small conductance. T-type channels are thought to be involved in pacemaker activity, low-threshold calcium spikes, neuronal oscillations and resonance, and rebound burst firing. Many alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Calcium Voltage-gated Channel Subunit Alpha1 G
Chromosome: CHR17: 48638448 -48704542
Locus: 17q21.33
LUC7L3 Gene Summary
This gene encodes a protein with an N-terminal half that contains cysteine/histidine motifs and leucine zipper-like repeats, and the C-terminal half is rich in arginine and glutamate residues (RE domain) and arginine and serine residues (RS domain). This protein localizes with a speckled pattern in the nucleus, and could be involved in the formation of splicesome via the RE and RS domains. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2009]
Gene Name: LUC7 Like 3 Pre-mRNA Splicing Factor
Chromosome: CHR17: 48796925 -48830072
Locus: 17q21.33
Gene Diseases
The LUC7L3 CACNA1G Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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