LSR-NLRP2 Fusion FISH Probe
The LSR-NLRP2 Fusion FISH Probe is used to confirm a fusion of the LSR and NLRP2 genes. The fusion of the LSR and NLRP2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LSR-NLRP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| LSR-NLRP2-20-AQAQ | 20 (40 μL) | 200 μL |
|
LSR Gene Summary
The Lipolysis Stimulated Lipoprotein Receptor (LSR) gene is located on chr19 :35739558-35758867 at 19q13.12.
Gene Name: Lipolysis Stimulated Lipoprotein Receptor
Chromosome: CHR19: 35739558 -35758867
Locus: 19q13.12
NLRP2 Gene Summary
This gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Gene Name: NLR Family Pyrin Domain Containing 2
Chromosome: CHR19: 55476651 -55512510
Locus: 19q13.42
Gene Diseases
The LSR NLRP2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|