LSM14A-KNDC1 Fusion FISH Probe
The LSM14A-KNDC1 Fusion FISH Probe is used to confirm a fusion of the LSM14A and KNDC1 genes. The fusion of the LSM14A and KNDC1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LSM14A-KNDC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-RERE | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-REOR | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-REGO | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-REGR | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-REAQ | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-ORRE | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-OROR | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-ORGO | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GORE | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GOOR | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GOGO | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GOGR | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GRRE | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GROR | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GRGO | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GRGR | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-AQRE | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-AQOR | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-AQGO | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-AQGR | 20 (40 μL) | 200 μL |
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| LSM14A-KNDC1-20-AQAQ | 20 (40 μL) | 200 μL |
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LSM14A Gene Summary
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]
Gene Name: LSM14A, MRNA Processing Body Assembly Factor
Chromosome: CHR19: 34663351 -34720420
Locus: 19q13.11
KNDC1 Gene Summary
The protein encoded by this gene is a Ras guanine nucleotide exchange factor that appears to negatively regulate dendritic growth in the brain. Knockdown of this gene in senescent umbilical vein endothelial cells partially reversed the senescence, showing that this gene could potentially be targeted by anti-aging therapies. [provided by RefSeq, Dec 2016]
Gene Name: Kinase Non-catalytic C-lobe Domain Containing 1
Chromosome: CHR10: 134973970 -135039916
Locus: 10q26.3
Gene Diseases
The LSM14A KNDC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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