LSAMP-COL4A5 Fusion FISH Probe
The LSAMP-COL4A5 Fusion FISH Probe is used to confirm a fusion of the LSAMP and COL4A5 genes. The fusion of the LSAMP and COL4A5 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LSAMP-COL4A5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-RERE | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-REOR | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-REGO | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-REGR | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-REAQ | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-ORRE | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-OROR | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-ORGO | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-ORAQ | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GORE | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GOOR | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GOGO | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GOGR | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GOAQ | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GRRE | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GROR | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GRGO | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GRGR | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-GRAQ | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-AQRE | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-AQOR | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-AQGO | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-AQGR | 20 (40 μL) | 200 μL |
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| LSAMP-COL4A5-20-AQAQ | 20 (40 μL) | 200 μL |
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COL4A5 Gene Summary
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]
Gene Name: Collagen Type IV Alpha 5 Chain
Chromosome: CHRX: 107683153 -107940775
Locus: Xq22.3
LSAMP Gene Summary
This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: Limbic System-associated Membrane Protein
Chromosome: CHR3: 115521209 -116164385
Locus: 3q13.31
Gene Diseases
The LSAMP COL4A5 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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