LRRC61-DOCK4 Fusion FISH Probe
The LRRC61-DOCK4 Fusion FISH Probe is used to confirm a fusion of the LRRC61 and DOCK4 genes. The fusion of the LRRC61 and DOCK4 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRRC61-DOCK4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-RERE | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-REOR | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-REGO | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-REGR | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-REAQ | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-ORRE | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-OROR | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-ORGO | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-ORAQ | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GORE | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GOOR | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GOGO | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GOGR | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GOAQ | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GRRE | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GROR | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GRGO | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GRGR | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-GRAQ | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-AQRE | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-AQOR | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-AQGO | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-AQGR | 20 (40 μL) | 200 μL |
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| LRRC61-DOCK4-20-AQAQ | 20 (40 μL) | 200 μL |
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DOCK4 Gene Summary
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008]
Gene Name: Dedicator Of Cytokinesis 4
Chromosome: CHR7: 111366163 -111846462
Locus: 7q31.1
LRRC61 Gene Summary
The Leucine Rich Repeat Containing 61 (LRRC61) gene is located on chr7 :150020295-150035245 at 7q36.1.
Gene Name: Leucine Rich Repeat Containing 61
Chromosome: CHR7: 150020295 -150035245
Locus: 7q36.1
Gene Diseases
The LRRC61 DOCK4 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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