LRRC20-NODAL Fusion FISH Probe
The LRRC20-NODAL Fusion FISH Probe is used to confirm a fusion of the LRRC20 and NODAL genes. The fusion of the LRRC20 and NODAL genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRRC20-NODAL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-RERE | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-REOR | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-REGO | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-REGR | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-REAQ | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-ORRE | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-OROR | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-ORGO | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-ORAQ | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GORE | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GOOR | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GOGO | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GOGR | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GOAQ | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GRRE | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GROR | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GRGO | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GRGR | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-GRAQ | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-AQRE | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-AQOR | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-AQGO | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-AQGR | 20 (40 μL) | 200 μL |
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| LRRC20-NODAL-20-AQAQ | 20 (40 μL) | 200 μL |
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NODAL Gene Summary
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016]
Gene Name: Nodal Growth Differentiation Factor
Chromosome: CHR10: 72191691 -72201465
Locus: 10q22.1
LRRC20 Gene Summary
The Leucine Rich Repeat Containing 20 (LRRC20) gene is located on chr10 :72058728-72142382 at 10q22.1.
Gene Name: Leucine Rich Repeat Containing 20
Chromosome: CHR10: 72058728 -72142382
Locus: 10q22.1
Gene Diseases
The LRRC20 NODAL Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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