LRRC1-SH3GL1 Fusion FISH Probe
The LRRC1-SH3GL1 Fusion FISH Probe is used to confirm a fusion of the LRRC1 and SH3GL1 genes. The fusion of the LRRC1 and SH3GL1 genes has been associated with Brain Lower Grade Glioma, and Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRRC1-SH3GL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-RERE | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-REOR | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-REGO | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-REGR | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-REAQ | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-ORRE | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-OROR | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-ORGO | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GORE | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GOOR | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GOGO | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GOGR | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GRRE | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GROR | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GRGO | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GRGR | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-AQRE | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-AQOR | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-AQGO | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-AQGR | 20 (40 μL) | 200 μL |
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| LRRC1-SH3GL1-20-AQAQ | 20 (40 μL) | 200 μL |
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SH3GL1 Gene Summary
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Gene Name: SH3 Domain Containing GRB2 Like 1, Endophilin A2
Chromosome: CHR19: 4360363 -4400565
Locus: 19p13.3
LRRC1 Gene Summary
The Leucine Rich Repeat Containing 1 (LRRC1) gene is located on chr6 :53659777-53788919 at 6p12.1.
Gene Name: Leucine Rich Repeat Containing 1
Chromosome: CHR6: 53659777 -53788919
Locus: 6p12.1
Gene Diseases
The LRRC1 SH3GL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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