LRP8-TMEM217 Fusion FISH Probe
The LRP8-TMEM217 Fusion FISH Probe is used to confirm a fusion of the LRP8 and TMEM217 genes. The fusion of the LRP8 and TMEM217 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRP8-TMEM217-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-RERE | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-REOR | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-REGO | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-REGR | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-REAQ | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-ORRE | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-OROR | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-ORGO | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-ORAQ | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GORE | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GOOR | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GOGO | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GOGR | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GOAQ | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GRRE | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GROR | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GRGO | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GRGR | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-GRAQ | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-AQRE | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-AQOR | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-AQGO | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-AQGR | 20 (40 μL) | 200 μL |
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| LRP8-TMEM217-20-AQAQ | 20 (40 μL) | 200 μL |
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LRP8 Gene Summary
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011]
Gene Name: LDL Receptor Related Protein 8
Chromosome: CHR1: 53708040 -53793821
Locus: 1p32.3
TMEM217 Gene Summary
The Transmembrane Protein 217 (TMEM217) gene is located on chr6 :37179953-37225413 at 6p21.2.
Gene Name: Transmembrane Protein 217
Chromosome: CHR6: 37179953 -37225413
Locus: 6p21.2
Gene Diseases
The LRP8 TMEM217 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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