LRP5-VPS26B Fusion FISH Probe
The LRP5-VPS26B Fusion FISH Probe is used to confirm a fusion of the LRP5 and VPS26B genes. The fusion of the LRP5 and VPS26B genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRP5-VPS26B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-RERE | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-REOR | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-REGO | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-REGR | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-REAQ | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-ORRE | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-OROR | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-ORGO | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-ORAQ | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GORE | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GOOR | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GOGO | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GOGR | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GOAQ | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GRRE | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GROR | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GRGO | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GRGR | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-GRAQ | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-AQRE | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-AQOR | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-AQGO | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-AQGR | 20 (40 μL) | 200 μL |
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| LRP5-VPS26B-20-AQAQ | 20 (40 μL) | 200 μL |
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LRP5 Gene Summary
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: LDL Receptor Related Protein 5
Chromosome: CHR11: 68080107 -68216743
Locus: 11q13.2
VPS26B Gene Summary
The VPS26, Retromer Complex Component B (VPS26B) gene is located on chr11 :134094560-134117686 at 11q25.
Gene Name: VPS26, Retromer Complex Component B
Chromosome: CHR11: 134094560 -134117686
Locus: 11q25
Gene Diseases
The LRP5 VPS26B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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