LRP5-CHD6 Fusion FISH Probe
The LRP5-CHD6 Fusion FISH Probe is used to confirm a fusion of the LRP5 and CHD6 genes. The fusion of the LRP5 and CHD6 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRP5-CHD6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-RERE | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-REOR | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-REGO | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-REGR | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-REAQ | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-ORRE | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-OROR | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-ORGO | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-ORAQ | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GORE | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GOOR | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GOGO | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GOGR | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GOAQ | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GRRE | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GROR | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GRGO | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GRGR | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-GRAQ | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-AQRE | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-AQOR | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-AQGO | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-AQGR | 20 (40 μL) | 200 μL |
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| LRP5-CHD6-20-AQAQ | 20 (40 μL) | 200 μL |
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LRP5 Gene Summary
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: LDL Receptor Related Protein 5
Chromosome: CHR11: 68080107 -68216743
Locus: 11q13.2
CHD6 Gene Summary
This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]
Gene Name: Chromodomain Helicase DNA Binding Protein 6
Chromosome: CHR20: 40031169 -40247133
Locus: 20q12
Gene Diseases
The LRP5 CHD6 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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