LRCH3-FMN2 Fusion FISH Probe
The LRCH3-FMN2 Fusion FISH Probe is used to confirm a fusion of the LRCH3 and FMN2 genes. The fusion of the LRCH3 and FMN2 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRCH3-FMN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-RERE | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-REOR | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-REGO | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-REGR | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-REAQ | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-ORRE | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-OROR | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-ORGO | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GORE | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GOOR | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GOGO | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GOGR | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GRRE | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GROR | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GRGO | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GRGR | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-AQRE | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-AQOR | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-AQGO | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-AQGR | 20 (40 μL) | 200 μL |
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| LRCH3-FMN2-20-AQAQ | 20 (40 μL) | 200 μL |
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FMN2 Gene Summary
This gene is a member of the formin homology protein family. The encoded protein is thought to have essential roles in organization of the actin cytoskeleton and in cell polarity. This protein mediates the formation of an actin mesh that positions the spindle during oogenesis and also regulates the formation of actin filaments in the nucleus. This protein also forms a perinuclear actin/focal-adhesion system that regulates the shape and position of the nucleus during cell migration. Mutations in this gene have been associated with infertility and also with an autosomal recessive form of intellectual disability (MRT47). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jul 2017]
Gene Name: Formin 2
Chromosome: CHR1: 240255184 -240638489
Locus: 1q43
LRCH3 Gene Summary
The Leucine Rich Repeats And Calponin Homology Domain Containing 3 (LRCH3) gene is located on chr3 :197518144-197598456 at 3q29.
Gene Name: Leucine Rich Repeats And Calponin Homology Domain Containing 3
Chromosome: CHR3: 197518144 -197598456
Locus: 3q29
Gene Diseases
The LRCH3 FMN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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