LRBA-DLG2 Fusion FISH Probe
The LRBA-DLG2 Fusion FISH Probe is used to confirm a fusion of the LRBA and DLG2 genes. The fusion of the LRBA and DLG2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LRBA-DLG2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-RERE | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-REOR | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-REGO | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-REGR | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-REAQ | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-ORRE | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-OROR | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-ORGO | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GORE | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GOOR | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GOGO | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GOGR | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GRRE | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GROR | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GRGO | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GRGR | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-AQRE | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-AQOR | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-AQGO | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-AQGR | 20 (40 μL) | 200 μL |
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| LRBA-DLG2-20-AQAQ | 20 (40 μL) | 200 μL |
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LRBA Gene Summary
The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Name: LPS Responsive Beige-like Anchor Protein
Chromosome: CHR4: 151185810 -151936649
Locus: 4q31.3
DLG2 Gene Summary
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. [provided by RefSeq, Dec 2008]
Gene Name: Discs Large MAGUK Scaffold Protein 2
Chromosome: CHR11: 83166055 -85338314
Locus: 11q14.1
Gene Diseases
The LRBA DLG2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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