LPP-KCNIP4 Fusion FISH Probe
The LPP-KCNIP4 Fusion FISH Probe is used to confirm a fusion of the LPP and KCNIP4 genes. The fusion of the LPP and KCNIP4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LPP-KCNIP4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-RERE | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-REOR | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-REGO | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-REGR | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-REAQ | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-ORRE | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-OROR | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-ORGO | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-ORAQ | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GORE | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GOOR | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GOGO | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GOGR | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GOAQ | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GRRE | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GROR | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GRGO | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GRGR | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-GRAQ | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-AQRE | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-AQOR | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-AQGO | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-AQGR | 20 (40 μL) | 200 μL |
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| LPP-KCNIP4-20-AQAQ | 20 (40 μL) | 200 μL |
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LPP Gene Summary
This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: LIM Domain Containing Preferred Translocation Partner In Lipoma
Chromosome: CHR3: 187871662 -188608460
Locus: 3q27.3-q28
KCNIP4 Gene Summary
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Potassium Voltage-gated Channel Interacting Protein 4
Chromosome: CHR4: 20730238 -21950374
Locus: 4p15.31-p15.2
Gene Diseases
The LPP KCNIP4 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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