LPP-CLPTM1L Fusion FISH Probe
The LPP-CLPTM1L Fusion FISH Probe is used to confirm a fusion of the LPP and CLPTM1L genes. The fusion of the LPP and CLPTM1L genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LPP-CLPTM1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-RERE | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-REOR | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-REGO | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-REGR | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-REAQ | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-ORRE | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-OROR | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-ORGO | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GORE | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GOOR | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GOGO | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GOGR | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GRRE | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GROR | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GRGO | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GRGR | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-AQRE | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-AQOR | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-AQGO | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-AQGR | 20 (40 μL) | 200 μL |
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| LPP-CLPTM1L-20-AQAQ | 20 (40 μL) | 200 μL |
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LPP Gene Summary
This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: LIM Domain Containing Preferred Translocation Partner In Lipoma
Chromosome: CHR3: 187871662 -188608460
Locus: 3q27.3-q28
CLPTM1L Gene Summary
The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015]
Gene Name: CLPTM1 Like
Chromosome: CHR5: 1317999 -1345002
Locus: 5p15.33
Gene Diseases
The LPP CLPTM1L Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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