LPHN3-AMTN Fusion FISH Probe
The LPHN3-AMTN Fusion FISH Probe is used to confirm a fusion of the LPHN3 and AMTN genes. The fusion of the LPHN3 and AMTN genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LPHN3-AMTN-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-RERE | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-REOR | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-REGO | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-REGR | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-REAQ | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-ORRE | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-OROR | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-ORGO | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-ORAQ | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GORE | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GOOR | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GOGO | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GOGR | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GOAQ | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GRRE | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GROR | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GRGO | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GRGR | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-GRAQ | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-AQRE | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-AQOR | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-AQGO | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-AQGR | 20 (40 μL) | 200 μL |
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| LPHN3-AMTN-20-AQAQ | 20 (40 μL) | 200 μL |
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AMTN Gene Summary
The mineralized portions of teeth, the dentin and enamel, are formed by mesenchyme-derived odontoblasts and epithelium-derived ameloblasts, respectively. As ameloblasts differentiate, they deposit specific proteins necessary for enamel formation, including amelogenin (AMELX; MIM 300391), enamelin (ENAM; MIM 606585), and ameloblastin (AMBN; MIM 601259), in the organic enamel matrix. Amelotin is specifically expressed in maturation-stage ameloblasts (Iwasaki et al., 2005 [PubMed 16304441]).[supplied by OMIM, Mar 2008]
Gene Name: Amelotin
Chromosome: CHR4: 71384297 -71398459
Locus: 4q13.3
Gene Diseases
The LPHN3 AMTN Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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