LPCAT4-SPRED1 Fusion FISH Probe
The LPCAT4-SPRED1 Fusion FISH Probe is used to confirm a fusion of the LPCAT4 and SPRED1 genes. The fusion of the LPCAT4 and SPRED1 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LPCAT4-SPRED1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-RERE | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-REOR | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-REGO | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-REGR | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-REAQ | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-ORRE | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-OROR | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-ORGO | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-ORAQ | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GORE | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GOOR | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GOGO | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GOGR | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GOAQ | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GRRE | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GROR | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GRGO | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GRGR | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-GRAQ | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-AQRE | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-AQOR | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-AQGO | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-AQGR | 20 (40 μL) | 200 μL |
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| LPCAT4-SPRED1-20-AQAQ | 20 (40 μL) | 200 μL |
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SPRED1 Gene Summary
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]
Gene Name: Sprouty Related EVH1 Domain Containing 1
Chromosome: CHR15: 38545051 -38649450
Locus: 15q14
LPCAT4 Gene Summary
Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]).[supplied by OMIM, May 2008]
Gene Name: Lysophosphatidylcholine Acyltransferase 4
Chromosome: CHR15: 34651088 -34659395
Locus: 15q14
Gene Diseases
The LPCAT4 SPRED1 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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