LPCAT2-DNAJA2 Fusion FISH Probe
The LPCAT2-DNAJA2 Fusion FISH Probe is used to confirm a fusion of the LPCAT2 and DNAJA2 genes. The fusion of the LPCAT2 and DNAJA2 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LPCAT2-DNAJA2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-RERE | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-REOR | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-REGO | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-REGR | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-REAQ | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-ORRE | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-OROR | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-ORGO | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-ORAQ | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GORE | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GOOR | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GOGO | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GOGR | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GOAQ | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GRRE | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GROR | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GRGO | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GRGR | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-GRAQ | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-AQRE | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-AQOR | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-AQGO | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-AQGR | 20 (40 μL) | 200 μL |
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| LPCAT2-DNAJA2-20-AQAQ | 20 (40 μL) | 200 μL |
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DNAJA2 Gene Summary
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq, Jul 2008]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member A2
Chromosome: CHR16: 46989273 -47007625
Locus: 16q11.2
LPCAT2 Gene Summary
This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009]
Gene Name: Lysophosphatidylcholine Acyltransferase 2
Chromosome: CHR16: 55542912 -55620582
Locus: 16q12.2
Gene Diseases
The LPCAT2 DNAJA2 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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